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Psychedelic Definition & Meaning Kast and Collins found that LSD had an analgesic effect at least comparable to opiates, but that the LSD analgesia outlasted its acute psychologic effects. Subsequent study revealed that patients treated with LSD had improved psychologic adjustment, were more responsive to their families and environments, and had enhanced ability to enjoy everyday life . With respect to treatment of dying cancer patients, this group found that about two-thirds of cancer patients who received LSD treatment had improved mood and reduced anxiety and fear of death (Pahnke et al., 1969, 1970b; Grof et al., 1973). In a subsequent study, Kyzar et al. studied the effect of mescaline (5–20 mg/l) on zebrafish behavior in the novel tank test, open field, and shoaling tests. Treatment consisted of psychosocial treatment only, psychosocial treatment coupled with psilocybin, and post-treatment follow-up. There was no increase in abstinence during the first month of psychosocia...